The Prepubertal Androgenic Response to ACTH
نویسندگان
چکیده
منابع مشابه
Response to ACTH in the newborn.
Adrenocortical function was studied in 52 newborn infants who had been divided into three groups: preterm well, preterm ill, and term ill. Basal plasma 17-hydroxyprogesterone concentrations were significantly increased in both groups of preterm infants. There was no significant difference in basal plasma cortisol concentrations, although they were highest in preterm ill infants. All infants res...
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During early pregnancy, progesterone stimulates the secretion of proteins and other molecules that support the developing conceptus. Some gilts are able to support conceptus development as early as 110 days of age. The objective of this study was to evaluate the onset of responsiveness of the prepubertal uterus to progesterone. Thirty gilts were assigned to receive 2.2 mg progesterone kg-1 body...
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The biochemical abnormalities in patients with "idiopathic hirsutism" are imperfectly understood. The fractionation and measurement of urinary 17ketosteroids in these patients have been studied in several laboratories. It appears that this disorder is associated with increased production of an adrenal androgen which is reflected by increased excretion of urinary C1902 17-ketosteroids, in partic...
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Angora goats do not cope well with stress compared with goats of other breeds. Our hypothesis that this involves subclinical primary hypoadrenocorticism associated with low cortisol release in response to ACTH stimulation was tested by measuring adrenocortical response (plasma cortisol) in six Spanish (37 +/- 2 kg BW) and six Angora wethers (39 +/- 3 kg BW) under simulated acute and chronic ACT...
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OBJECTIVE Agouti protein (AP) and agouti-related protein with a similar sequence and action are endogenous antagonists of melanocortin receptors, implicated in the control of the hypothalamo-pituitary-adrenal (HPA) axis. Dominant mutation of the agouti gene (agouti yellow (A(y))) in heterozygous A(y)/a mice leads to ectopic overexpression of AP and produces an obese phenotype. The existing data...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1970
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197009000-00100